品名: Zileuton

货号: N-3023-1

规格: 10 mg

品牌：rPeptide

储存温度：-20℃

序列：N/A

来源：N/A

描述：Reversible inhibitor of 5-Lipoxygenase (IC50 = 500 nM in RBL-1 cells and 300 nM rat PMNLs)[1]. It also inhibited leukotriene B4 biosynthesis (IC50's = 400nM rat PMNL, 400nM human PMNL)[1]. Zileuton suppressed prostaglandin biosynthesis via interference with arachidonic acid release in macrophages independent of 5-LO inhibition (IC50 = 13 μM PGE2 inhibition in LPS-stimulated whole blood)[2]. Restores memory impairments and reverses amyloid and tau pathology in an Alzheimer’s mouse model[3].

分子量：236.3

纯度：>98%