A/F Protein Inc., founded in 1994, specializes in the purification and supply of antifreeze proteins (AFPs) derived from natural sources for research applications. The study of antifreeze proteins dates back to the 1950s, when scientists discovered that certain fish can survive in subzero environments due to the presence of ice-binding proteins that lower the freezing point of bodily fluids. A/F Protein has established strong expertise in this field and holds multiple patents covering key applications of AFPs, including cryopreservation of mammalian cells, tissues, and organs, as well as the use of antifreeze proteins in cryoablation of tumor cells. The company’s core products include Type I and Type III antifreeze proteins and antifreeze glycoproteins, all purified from cold-water marine fish and supplied in dry form for research and development use.
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A/F Protein offers high-purity Type I and Type III antifreeze proteins, as well as antifreeze glycoproteins, purified from natural marine sources. These products are widely used in cryobiology and life science research, supporting applications such as low-temperature preservation of platelets, enhancement of tumor cryoablation, organ transplantation preservation solutions, and cryopreservation of reproductive cells including oocytes, sperm, and embryos. In addition, AFP-based technologies have potential applications in veterinary reproduction, skincare formulations for cold environments, and food processing for texture improvement and frozen preservation.
