Expression Systems develops innovative media formulations, supporting products, and contract services for the baculovirus, cell culture, and biomanufacturing markets. The company specializes in baculovirus/host cell systems with a strong focus on insect and mammalian cell culture. With deep expertise in the Baculovirus Expression Vector System (BEVS), Expression Systems supports researchers and clinical teams across academia, biotech, and pharma by enabling stable, consistent expression workflows. Its portfolio includes high-quality insect cell media and baculovirus products, chemically defined media, bioprocess buffers, molecular tools and reagents used in the production of candidate therapeutics, protein therapeutics, vaccines, and gene therapy-related applications. The company also provides contract services and baculovirus titer testing services to support biotech and research customers.

■ Product Portfolio

Vicbio Biotechnology Co., Ltd. provides the full range of Expression Systems products.

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■ Cell Culture Media

Media formulations designed to support growth and high productivity across major Lepidopteran cell lines (Sf9, Sf21, High Five™) and Dipteran cell lines (S2). Expression Systems also offers complete animal component–free media solutions for HEK293, CHO, and hybridoma culture. Key offerings include:

• ESF SFM (animal component–free mammalian SFM; optimized for suspension systems)

• ESF AdvanCD™ (chemically defined insect cell culture media)

• ESF 921 (protein-free insect cell culture media)

• ESF AF (animal component–free insect cell culture media)

• ESF 921 Delta series

• PBA insect cell production enhancer supplement

■ Cells

Selected high-quality insect and mammalian cell lines supplied as suspension-adapted cells or cryopreserved vials, including Sf9 RV-Free insect cells and other insect/mammalian cell options for diverse culture needs.

■ Reagents

Workflow reagents designed for insect cell expression and baculovirus work, including:

• PBA (production booster additive to improve expression yield)

• gp64-PE antibody (for detecting baculovirus gp64 membrane protein expression)

• Baculovirus titer assay kits and baculovirus titer testing services (for quantifying infectious baculovirus)

■ Molecular Tools

Molecular tools that streamline the path from gene-of-interest to protein expression, including plasmids, linearized DNA, and supporting reagents such as:

• BestBac™ linearized DNA (for co-transfection)

• pVL1392 / pVL1393 transfer vectors (insert gene-of-interest; co-transfect with BestBac to generate recombinants)

• Expres2TR transfection reagent (optimized for insect cells)

• Transfection media supporting co-transfection by enhancing DNA uptake

■ Bioprocess Buffers

Through its parent company Advancion, Expression Systems also offers a broad range of high-purity buffers, including cGMP grade* options such as TRIS AMINO, TRIS AMINO™ HCl, and HEPES, as well as general-purpose buffer solutions.

■ Product List