QA Bio, founded in 2012, is dedicated to providing specialized tools for glycan analysis to the biopharmaceutical manufacturing industry. Its products are used by biopharmaceutical companies worldwide in workflows associated with FDA- and EMA-approved programs. By optimizing chemical formulations, material selection, manufacturing processes, and storage conditions, QA Bio is committed to maintaining high standards of accuracy and reproducibility across its product range. All products are designed to provide convenient, fast, and user-friendly analytical solutions. The company’s core product categories include endoglycosidases, exoglycosidases, deglycosylation, sialic acid products, glycan labeling, capture and cleanup, standards, and columns and buffers.
■ Product Portfolio
Vicbio Biotechnology Co., Ltd. provides the full range of QA Bio products.
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●Endoglycosidases
Endoglycosidases are among the most widely used enzymes for glycoprotein analysis. These enzymes release intact glycans from glycoproteins, making them suitable for downstream glycan characterization workflows. QA Bio offers products such as PNGase F, recombinant PNGase F, Endo F1/F2/F3, Endo H, O-Glycosidase, and related kits in this category.
●Exoglycosidases
Exoglycosidases remove individual monosaccharides from the non-reducing ends of glycans. This product line supports detailed glycan structure analysis and includes enzymes such as neuraminidases, galactosidases, mannosidases, fucosidases, and glycan sequencing kits.
●Deglycosylation
QA Bio offers deglycosylation products for removing glycans from glycoproteins while preserving glycan integrity for further analysis. This category includes enzymatic deglycosylation kits, DeGlycoMx kits, O-linked glycan release kits, hydrazinolysis kits, and related workflow components.
●Sialic Acid Products
This category includes products for sialic acid analysis and quantitation, including labeling kits, reference panels, standards, and related enzymes. These products support the study of terminal sialic acid structures in both N-linked and O-linked glycans.
●Glycan Labeling
QA Bio provides glycan labeling products made with analytical-grade reagents and controlled handling processes. This product line includes procainamide labeling kits, 2-AB labeling kits, 2-AA labeling kits, permethylation kits, monosaccharide analysis kits, and glycopeptide labeling kits.
●Capture and Cleanup
QA Bio offers multiple products for glycan capture and cleanup after enzyme digestion and molecular labeling. Plates and cartridges are designed to bind glycans while allowing contaminants to be washed through, supporting efficient sample purification workflows.
●Glycan Analysis Standards
The company provides a variety of qualitative and quantitative glycan standards and glycoprotein standards for glycan analysis. These products are commonly used as markers and reference compounds in HPLC, HILIC, MS, HPAEC, and MALDI-TOF workflows in biopharmaceutical laboratories.
■ Product List
| Product name | Cat. # | Size |
| PNGase F | E-PNG01 | 20 µl; 60 µl; 200 µl |
| PNGase F – recombinant | E-RPNG01 | 20 µl; 60 µl; 200 µl |
| Endo F1 | E-EF01 | 20 µl; 60 µl; 200 µl |
| Endo F2 | E-EF02 | 20 µl; 60 µl; 200 µl |
| Endo F3 | E-EF03 | 20 µl; 60 µl; 200 µl |
| Endo F Multi-Kit | KE-EFX3 | 1 kit |
| Endo H | E-EH02 | 20 µl; 60 µl; 200 µl |
| O-Glycosidase | E-G001 | 20 µl; 60 µl; 200 µl |
| Endo-ß-Galactosidase | E-XBG01 | 20 µl; 60 µl; 200 µl |
| Ceramide Glycanase | LZ-CER-HM-KIT | 1 kit |
| α-(2-3,6,8,9) Neuraminidase Au | E-S001 | 20 µl; 60 µl; 200 µl |
| α-(2-3,6) Neuraminidase Cp | E-S005 | 20 µl; 60 µl; 200 µl |
| α-(2-3) Neuraminidase Sp | E-S007 | 20 µl; 60 µl; 200 µl |
| Acetyl Eseterase | LZ-ACASE-KIT | 50 µL |
| β-(1-4) Galactosidase-Sp | E-BG07 | 20 µl; 60 µl; 200 µl |
| β-(1-3,6) Galactosidase-Xan | E-BG06 | 20 µl; 60 µl; 200 µl |
| β-(1-3,4,6) Galactosidase-bt | E-BG02 | 200 µl |
| β-(1-3,4,6) Galactosidase-mx | E-BG05 | 20 µl; 60 µl; 200 µl |
| α-(1-3,6) Galactosidase | E-AG02 | 20 µl; 60 µl; 200 µl |
| N-Acetlyglucosaminidase | E-GL01 | 20 µl; 60 µl; 200 µl |
| α-(1-2,3,6) Mannosidase | E-AM01 | 20 µl; 60 µl; 200 µl |
| α-(1-6) Mannosidase | E-AM02 | 20 µl; 60 µl; 200 µl |
| α-(1-6) Fucosidase | E-F006 | 20 µl; 60 µl; 200 µl |
| α-(1-3,4) Fucosidase | E-F134 | 20 µl; 60 µl; 200 µl |
| Ludger α-(1-3,4) Fucosidase | LZ-FUCOSIDASE-01-KIT | 50 µL |
| Glycan Sequencing Kit | KE-SQ01 | 1 kit |
| Enzymatic Deglycosylation Kit | KE-DG01 | - |
| Enzymatic DeGlycoMx Kit | KE-DGMX | 20 µls; 100 µls |
| Orela O-Linked Glycan Release Kit | LL-ORELA-A2 | 1 kit |
| Orela Release Reagent | LL-ORELAREAGENT-0 | 2 x 3ml |
| Acetic Acid Solution | LL-ACETIC-50P-01 | 2 x 3ml |
| LudgerClean CEX-H cartridges | LC-CEX-H-01 | 2 x 6 cartridges |
| Collection vials with PTFE lined caps | LL-COLLV-01 | 2 x 6 vials |
| Reaction vials with PTFE lined caps | LL-REACT-01 | 2 x 6 vials |
| Hydrazinolysis Kit | LL-HYDRAZ-A2 | 1 kit |
| Sialidase Testing Panel | CAB-STP-NEUAC-01 | 2-AB |
| Sialidase Testing Panel | CPROC-STP-NEUAC-01 | procainamide |
| DMB Sialic Acid Labeling Kit | LT-KDMB | 12 samples; 22 samples; 96 samples |
| uR2 2.1x100mm UHPLC Column | LS-UR2-2.1×100 | 2.1mm x 100mm |
| Sialic Acid Quantitation Kit | KE-SIALIQ | 25 assays |
| Sialic Acid Aldolase | E-ALD01 | - |
| CMP-Sialic Acid Synthetase | E-CMP01 | - |
| Sialic Acid Reference Panel | CM-SRP-01 | approx. 1.25 nmols |
| BioQuant NANA standard | CM-NEU-AC | 1 nmol; 100 nmol |
| BioQuant NGNA Standard | CM-NEU-GC | 1 nmol; 100 nmol |
| Neu5,9Ac2 | CM-NEU5,9AC2-01 | ~1 nmol (of which 770 pmol is Neu5,9Ac2) |
| Procainamide Labeling Kit | LT-KPROC | Sodium Cyanoborohydride - 24 rxns; Sodium Cyanoborohydride - 96 rxns;2-Picoline Borane - 24 rxns |
| Permethylation Kit | LT-PERMET-VP96 | 2-Picoline Borane – 96 samples |
| 2-AB Labeling Kits | LT-KAB | Sodium Cyanoborohydride - 24 rxns; Sodium Cyanoborohydride - 96 rxns;2-Picoline Borane - 24 rxns |
| 2-AA Labeling Kit | LT-KAA | Sodium Cyanoborohydride - 24 rxns; 2-Picoline Borane - 24 rxns |
| Monosaccharide Analysis Kit | LT-MONO-96 | - |
| V-Tag Glycopeptide Labeling Kit | LT-VTAG-24 | - |
| Exoglycosidase Clean-up Plate | LC-EXO-96 | Up to 350 μL per column |
| Exoglycosidase Clean-up Cartridges | LC-EXO-A6 | Up to 500 μL per column |
| Glycopeptide Enrichment Cartridges | LC-A-24 | 24 cartridges |
| EC50 Plate | LC-EC50-96 | one 96-well plate |
| EC50 Cartridges | LC-EC50-24 | 24 cartridges |
| EB10 Cartridges | LC-EB10-A6 | 6 cartridges |
| CEX Cartridges for O-glycans | LC-CEX-A6 | 6 cartridges |
| Pre-Permethylation Cleanup Plate | LC-PERMET-96 | 96 samples |
| Procainamide Cleanup Plate | LC-PROC-96 | 96 samples |
| S Cartridges | LC-S-A6 | 6 cartridges |
| T1 Cartridges | LC-T1-A6 | 6 cartridges |
| Velocity Vacuum Manifold | LC-VAC-MANIFOLD-KIT | 1 kit |
| Velocity Vacuum Trap | LC-VAC-TRAP-KIT | 1 kit |
| Velocity Collection Plate | LP-COLLPLATE-2ML-96 | 96 wells |
| Velocity Collection Plate Lid | LP-COLLPLATE-LID-96 | 96 wells |
| Velocity Cartridge Holder | LP-HOLDER-96 | 96 wells |
| Velocity Plug Pack | LP-PLUG-96 | 12 strips of 8 plugs |
