Signosis is a bioassay-focused company dedicated to developing innovative products for biomarker discovery and analysis. Its core focus spans multiple key regulatory molecules, including transcription factors, cytokines, microRNAs, and disease biomarkers. The company provides assay products for disease-related proteins, mRNA, microRNA, epigenetic variation, and SNP-related studies, with applications across disease areas such as cancer, diabetes/obesity, and cardiovascular disease. Signosis also offers validated luciferase reporter stable cell lines for monitoring signaling pathway activity through transcription factor activation, as well as a broad range of overexpression stable cell lines including EGFR mutant models. In addition, the company provides custom services for assay kit development, outsourced testing and data analysis, and custom stable cell line generation. Official product pages highlight stable cell lines, TF assays, cytokine ELISA platforms, gene expression assays, and custom bioassay solutions as key parts of its portfolio. 

■ Product Portfolio

Vicbio Biotechnology Co., Ltd. provides the full range of Signosis products.

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●Stable Cell Lines

Stable cell lines are widely used in gene function analysis, target discovery and validation, assay development, and compound screening. Signosis provides a variety of gene expression-ready and luciferase reporter-ready stable cell lines to support cell-based research workflows. Official product information also highlights reporter stable cell lines for monitoring transcription factor activation, isoform-specific NHR reporter lines, GPCR luciferase reporter lines, and receptor tyrosine kinase mutation panels including EGFR variants. 

●Transcription Factor Assays

Signosis offers multiple assay formats for transcription factor research, including plate array systems for parallel TF profiling as well as tools for precise single-TF analysis. Its official TF assay portfolio includes TF activation assays, TF ELISA kits, EMSA-related reagents, luciferase reporter vectors, luciferase stable cell lines, and associated assay components.

●Cytokine ELISA

Signosis provides a series of cytokine detection tools for both single-target measurement and multiplex cytokine profiling. Official offerings include Cytokine ELISA Kits for individual cytokines, ELISA Strips for simultaneous detection of 8 cytokines, Mix & Match panels, and ELISA Plate Arrays capable of profiling 32 or more cytokines in one assay. 

●miRNA Research

Signosis provides innovative tools for miRNA research, including products for multi-miRNA expression profiling and specific single-miRNA detection workflows. Official product pages also show supporting components for miRNA Northern blot applications. 

●Gene Expression Analysis

Signosis offers a range of gene expression analysis products, including cDNA plate arrays for monitoring transcription factor-regulated gene expression and other assay tools for gene expression studies. Official descriptions state that these products are designed for studying genes that are up- or down-regulated under defined biological conditions. 

●Biomarkers and Key Proteins

Signosis provides a variety of ELISA kits for detecting biomarkers associated with autoimmune diseases, cardiovascular disease, and cancer. Its official cytokine and disease-focused assay pages also emphasize fast, sensitive, and quantitative biomarker detection across multiple sample types.

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