Bioventix plc specializes in the development and production of high-affinity sheep monoclonal antibodies (SMAs), primarily for diagnostic applications such as clinical blood testing and drugs-of-abuse testing. Compared with traditional rodent-derived monoclonal antibodies, sheep-derived monoclonal antibodies offer unique advantages in low-abundance target detection, short peptide sequence recognition, and the detection of small molecules and drug targets. In a wide range of assay formats, the use of high-affinity SMAs can help improve both sensitivity and accuracy. Bioventix offers antibody products covering areas such as cardiac disease, cancer, fertility monitoring, thyroid function, and drugs-of-abuse testing. Its core product lines include sheep monoclonal antibodies (SMAs), HOP-G ELISA kits, and HOP-G lateral flow assay kits.
■ Product Portfolio
Vicbio Biotechnology Co., Ltd. provides the full range of Bioventix products.
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●Sheep Monoclonal Antibodies (SMAs)
High-affinity sheep monoclonal antibodies designed for diagnostic and research applications, with particular advantages in low-level target detection, short peptide recognition, and small molecule or drug-targeted analysis.
●HOP-G ELISA Kits
ELISA-based assay kits developed for HOP-G detection and related testing applications.
●MHOP-G Lateral Flow Assay Kits
Lateral flow assay kits designed for rapid HOP-G detection in convenient test formats.
■ Product List
| Reactivity | Description | Designation |
| Tri-iodothyroxine (T3) | Useful for ultra-sensitive detection of free-T3 (FT3) | T3.17C6r |
| Thyroxine (T4) | For thyroid function tests Bind many commercially available T4 conjugates | T4.1C4 |
| Thyroid Stimulating Hormone (TSH) | Epitope 1. Forms part of the thyroid function testing panel. | TSH.1H11, TSH.6C10 |
| Thyroid Stimulating Hormone (TSH) | Epitope 2. Can pair with other TSH Abs. | TSH.6C9, TSH.11H5, TSH.12C7 |
| Thyroid Stimulating Hormone (TSH) | Epitope 3 | TSH.4C3 |
| Thyroid Stimulating Hormone (TSH) | Epitope 4 | TSH.6F11 |
| Parathyroid Hormone | Binds the N-terminal PTH and the biologically active PTH | PTH.3E8 (N-terminal aa1-6) |
| Parathyroid Hormone | Binds mid-molecule PTH. Epitope is different to PTH.1D4. | PTH.1B9 (Mid-region aa44-68) |
| Parathyroid Hormone | Binds mid-molecule PTH. Can pair with PTH.1B9. | PTH.1D4 (Mid-region aa44-68) |
| Parathyroid Hormone | Binds to C-terminal PTH. Pairs well with PTH.3E8. | PTH.3B8 (C-terminal aa64-84) |
| 25-Hydroxy D2 | Binds 25-Hydroxy vitamin D2 conjugates | VitD2.2D10 |
| 25-Hydroxy D3 | Binds 25-Hydroxy vitamin D3 conjugates | VitD3.2F4 |
| Total 25-Hydroxy D2+D3 | Binds 25(OH) D2/D3 equally. Useful for total vitamin D testing in serum or plasma. | VitD3.5H10 |
| Brain Natriuretic Peptide | Binds region bounded by amino acids 10-26, “loop” | BNP.3E7 |
| Brain Natriuretic Peptide | Binds C-terminus amino acids 27-32 | BNP.4H8 |
| Tetrahydrocannabinol (THC) | Useful for detecting cannabis use | THC.5B7 |
| Tetrahydrocannabinol (THC) | Binds THC in oral fluids | THC.2B9 |
| Buprenorphine | Useful in monitoring treatment with buprenorphine for opioid addiction | BUP.1C5 |
| Buprenorphine | Most sensitive detection of buprenorphine and metabolites in saliva | BUP.3G11 |
| Benzodiazepines | Measurement of ‘benzos’ is useful as part of general drugs of abuse screening | benzo.10G10 and others |
| Ethyl Glucoride (EtG) | Used for alcohol abuse monitoring | EtG.1E6 |
| Estrone (E1) | Useful to monitor low-dose female hormone replacement therapy in postmenopausal women. Useful to reduce undesirable estrone cross-reactivity in E2 assays. | E1.3H11r |
| Estradiol (E2) | Useful to investigate menstrual abnormalities. Estrone cross-reactivity can be blocked by E1.3H11. | E2.5A11 |
| Estradiol (E2) | E2.2C7 | |
| Estradiol (E2) | Has low estrone cross-reactivity | E2.6H9 |
| Estriol (E3) | Useful in second trimester monitoring in pregnancy | E3.8A4 |
| Estriol (E3) | E3.12G3 | |
| Progesterone | Useful for fertility monitoring. Prog.3H3 has been raised against a prog-11-BSA conjugate. | Prog.3H3 |
| Testosterone | Excellent sensitivity and precision in testosterone detection in both men and women | Testo3.6A3 |
| Androstenedione | Suitable for monitoring androstenedione levels in females | Andro.3C3 |
| Adrenocorticotropic Hormone | Useful for detecting adrenal insufficiency | ACTH.8A11 (N-term) |
| Adrenocorticotropic Hormone | Binds to cosyntropin | ACTH.7E7 (Middle) |
| Adrenocorticotropic Hormone | Binds the CLIP region of ACTH | ACTH.9F7 (C-term) |
| Human Chorionic Gonadotrophin (hCG) | - | hCG.11E7 |
| Human Chorionic Gonadotrophin (hCG) | - | hCG.4F9, hCG.8F11 |
| Human Chorionic Gonadotrophin (hCG) | - | hCG.12F6 |
| D-biotin | Binds to biotin with super-high affinity similar to avidin-biotin | DBt.1D10 |
| L-biotin | Binds the Laevo form of biotin. No interference by endogenous D-biotin. | LBt.1A7 |
| Cortisol | Binds cortisol and is used in tests to diagnose Cushing’s syndrome and Addison’s disease | cort.8F4 |
| Sheep FAb | Mouse monoclonal antibody (muMAb) binds to sheep FAb | ShFAb.1H6 |