Bio-Works was founded in 2006 and is a specialized manufacturer of WorkBeads™ chromatography resins and GoBio™ prepacked chromatography columns for the purification of monoclonal antibodies, proteins, peptides, oligonucleotides, viruses, and vaccines. WorkBeads resins are based on a unique porous bead formulation with tightly controlled particle size and pore size distribution, providing excellent purity, high binding capacity, and high flow performance for both small-scale research and large-scale industrial production. The company’s manufacturing, research and development, and sales operations are based in Uppsala, Sweden, and its quality management system is certified to ISO 9001 standards. Bio-Works offers a product portfolio including WorkBeads chromatography resins, bulk resins, and prepacked chromatography columns.

■ Product Portfolio

Vicbio Biotechnology Co., Ltd. provides the full range of Bioworks products.

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●Affinity Chromatography Resins

Optimized alkali-stable Protein A resins for laboratory purification of monoclonal and polyclonal antibodies, featuring a high-performance base matrix and a patented alkali-stable Protein A ligand for high dynamic binding capacity at short residence times.

●WorkBeads 40 Butyl SH-HIC Resin

A resin for hydrophobic interaction chromatography (HIC), designed for research and industrial-scale purification based on differences in the surface hydrophobicity of proteins, peptides, plasmids, and oligonucleotides. It can be used to complement separation techniques based on charge or size.

●GoBio™ Mini Columns

Available in 1 mL and 5 mL formats and packed with WorkBeads™ resins, suitable for efficient small-scale purification and early-stage process development screening.

●Ion Exchange Chromatography (IEX) Resins

High-resolution IEX resins designed for research and industrial-scale purification based on differences in the surface charge of proteins, peptides, and oligonucleotides. These resins provide high-resolution separation with low back pressure, making them suitable for capture and polishing applications in standard bioprocess chromatography columns.

●Immobilized Metal Affinity Chromatography (IMAC) Resins

WorkBeads™ IMAC resins enable rapid purification of His-tagged proteins and other proteins with affinity for metal ions.

●GoBio Prepacked Columns

Designed to support linear scale-up from process validation to commercial manufacturing and GMP production. These prepacked columns offer high scalability, increased throughput, and improved productivity, while helping facilities improve efficiency by reducing in-house column packing demands and shortening turnaround times.

●Size Exclusion Chromatography Resins

Agarose-based resins for biomolecule separation. WorkBeads resins are crosslinked using proprietary methods to create a highly rigid structure. Their rigidity and narrow particle size distribution allow purification of viruses and other large biomolecules at high flow rates, enabling fast processing and high yield.

●Pre-Activated Resins

Designed for convenient and effective ligand immobilization without the need for complex synthesis or specialized equipment. Two different pre-activated resins are available, in which bromopropane active groups react with thiol, amino, and hydroxyl groups on the ligand. Different resin porosities are available to support optimized coupling for ligands of different sizes and the preparation of affinity resins for targets of different molecular sizes.

●Bio-Works HTPD

Miniaturized robotic column formats designed to support high-throughput process development. RoboColumn® products are prepacked with Bio-Works WorkBeads resins and enable parallel screening of chromatography conditions in automated workflows.

●GoBio™ Mini Screening Kits

Screening kits designed for fast and convenient setup of resin and condition screening experiments.

●Desalting Columns

Designed for easy removal of salts from protein samples. WorkBeads™ Dsalt resins enable rapid and simple separation of high-molecular-weight and low-molecular-weight substances. They are suitable for effective desalting and buffer exchange of proteins, large peptides, and nucleic acids before or after purification steps. Chromatographic desalting can be performed at high flow rates and can be scaled up for bioproduction.

■ Product List