HyClone Defined Fetal Bovine Serum (FBS), US Origin

货号：sh30070.03

【产品说明】

Our highest quality FBS, HyClone US-origin defined FBS is 40 nm-filtered, virus-tested to meet 9 CFR, with an extensive biochemical profile.

【产品概述】

Our highest quality FBS, HyClone US-origin defined FBS is 40 nm-filtered, virus-tested to 9 CFR standard, and supplied with an extensive biochemical profile.

Well-defined: assay results for over 50 components, with additional testing available

US origin: sourced and processed in the United States with complete traceability to origin

Ultra-low endotoxin: ≤ 10 EU/mL endotoxin for reduced research and production risk

Sterile-filtered: serial 40 nm filter process removes up to 8 logs viral challenge

Post-filtration treatments: γ-irradiated and heat-inactivated FBS options also available

Virus-tested: broad virus panel testing in accordance with 9 CFR 113.53

Purchase orders with specific lot requests, quoted reserves and/or call off orders should be submitted through Customer Service.

Fetal bovine serum (FBS) is a nutrient-rich cell culture supplement that is high in growth factors and low in antibodies, compared to non-fetal sera.

Defined FBS for cell culture confidence and consistency

HyCloneTM Defined FBS is widely used by cell culturists who have a concern for viral contaminants and require an extensive biochemical profile. The final serum is assayed for over 50 components, including proteins, hormones, growth factors, metabolites, and nutrients important for cell culture. Assay results are included in the certificate of analysis and the biochemical assay list. Additional testing, including EMEA conformance testing, is also available.

Exceptionally low endotoxin levels

Endotoxin contamination is a significant concern when producing cell culture-derived products for use in humans or animals. The presence of endotoxin in cell cultures can also have adverse and unpredictable effects on cell growth, function and phenotype that can compromise research results. Our patented closed-system blood collection method and rigorous quality control testing ensure that HyClone defined FBS contains ≤ 10 EU/mL endotoxin and ≤ 10 mg/dL hemoglobin. Low hemoglobin levels in the final product are an indication that extensive cell lysis has not occurred, confirming that the fetal blood has been handled appropriately during collection and transport.

Virus-tested and quality-assured for reduced contamination risk

HyClone Defined FBS is filtered through serial 40 nm (0.04 μm) pore size-rated filters, which are the most retentive filters used in commercial FBS production. This type of filtration is a practical, cost-competitive method of viral load reduction.

Research shows that 40 nm filtration will remove as many as eight logs of viral challenge. Studies demonstrate that this filtration regimen has no adverse effect on cell growth. Before dispensing, each lot of serum is pooled using true pool technology to ensure uniformity and consistency between bottles.

The final serum is virus-tested according to 9 CFR 113.53 to demonstrate that there are no detectable levels of specified viruses, pathogenic agents, and hemadsorbing agents. Robust sterility testing further confirms that the final product contains no detectable growth of bacteria or fungi (current USP) and no detectable mycoplasma.

Post-filtration treatments for added process security

Gamma-irradiated and heat-inactivated FBS options are available to further reduce the risk of adventitious agents, particularly when manufacturing products for use in humans or animals. The irradiation process is validated to deliver a minimum dose of 25 kGy.

Regulatory and supply chain security

For decades, Cytiva's HyClone premium bovine serum products have exceeded industry standards for quality, purity, and regulatory compliance. HyClone serum processes are traceability-certified by the International Serum Industry Association (ISIA). In addition, Cytiva has chosen to be an early adopter of scientific traceability by Oritain to prove the country of origin of their premium bovine serum products from the United States, Australia, and New Zealand. Premium bovine serum samples from different regions have been analyzed and Oritain has created a database of the unique ‘Origin Fingerprint’ that is exclusive to each country of origin. Learn more.

【价格信息】

SH30070.03IH25-40

HyClone Defined FBS, US Origin, 500 mL, Irradiated 25-40kGy, Heat-inactivated

500 mL Online Offer

708.50 USD

SH30070.03IH30-45

HyClone Defined FBS, US Origin, 500 mL, Irradiated 30-45kGy, Heat-inactivated

500 mL Online Offer

708.50 USD

SH30070.03IR25-40

HyClone Defined FBS, US Origin, 500 mL, Irradiated 25-40kGy

500 mL Online Offer

692.69 USD

SH30070.02IR25-40

HyClone Defined FBS, US Origin, 100 mL, Irradiated 25-40kGy

100 mL On Request

SH30070.02IH25-40

HyClone Defined FBS, US Origin, 100 mL, Irradiated 25-40kGy, Heat-inactivated

100 mL On Request

SH30070.03IR30-45

HyClone Defined FBS, US Origin, 500 mL, Irradiated 30-45kGy

500 mL Online Offer

692.69 USD

SH30070.03

HyClone Defined FBS, US Origin, 500 mL

500 mL Online Offer

673.54 USD

SH30070.03HI

HyClone Defined FBS, US Origin, 500 mL, Heat-inactivated

500 mL Online Offer

689.35 USD

SH30070.02HI

HyClone Defined FBS, US Origin, 100 mL, Heat-inactivated

100 mL 248.00 USD

SH30070.02

HyClone Defined FBS, US Origin, 100 mL

100 mL 232.00 USD

SH30070.01

HyClone Defined FBS, US Origin, 50 mL

50 mL 137.00 USD

SH30070.01HI

HyClone Defined FBS, US Origin, 50 mL, Heat-inactivated

50 mL 154.00 USD