货号: | CCND1-IGH-Split-20-ORGR | 规格: | |
品牌: | 热销产品 | 价格: | ¥ |
产品分类: | 热销产品 | 研究领域: | |
CAS编号: | 分子量: | ||
分子式: | 别名: | ||
储存条件: | 运输条件: | ||
货期: | 应用: | ||
说明书: | 备注: | ||
产品描述 | |||
CCND1/IGH Split Fusion FISH Probe CCND1-IGH-Split-20-ORGR 20 (40 μL) CCND1-IGH-Split-20-GOGR 20 (40 μL) CCND1-IGH-Split-20-REGR 20 (40 μL) Brand:Empire Genomics Our CCND1/IGH split probe is designed to detect fusions between CCND1 and IGH. To account for the high degree of cross homology in the region containing IGH, part of the IGH portion has been removed. The probe comes labeled in orange and green, but can be customized to meet your needs. Gene Background: CCND1-IGH fusion is generated by t(11;14)(q13.3;q32.3), which places CCND1 gene next to IGH, resulting in constitutive overexpression of CCND1. The fusion can be found in up to 95% of patients with mantle cell lymphomas (MCL), and is considered the genetic hallmark of this subtype of low-grade peripheral B-cell neoplasms. CCND1-IGH has also been identified in other lymphoproliferative disorders (LPDs), such as B-prolymphocytic leukemia (BLL), and, less frequently, in plasma cell myelomas and B-cell chronic lymphocytic leukemia (CLL). Product Details SKU Test Kits Buffer CCND1-IGH-Split-20-ORGR (Standard Design) 20 (40 μL) 200 μL CCND1-IGH-Split-20-GOGR 20 (40 μL) 200 μL CCND1-IGH-Split-20-REGR 20 (40 μL) 200 μL |