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Human FcRn (FCGRT & B2M) HEK293 Cell Line 人FcRn (FCGRT & B2M) HEK293过表达细胞系
靶点信息

Target: Fc gamma receptor and transporter & Beta-2-microglobulin Alias: FcgammaRn, FcRn
FcRn(新生儿Fc受体)与β2-微球蛋白(B2M)形成稳定的异二聚体复合物,是IgG和白蛋白体内循环的重要调控因子。FcRn可通过pH依赖性结合保护IgG和白蛋白免于溶酶体降解,从而延长其半衰期。 |
产品信息
人FcRn (FCGRT & B2M) HEK293过表达细胞系是一种重组细胞系,经工程化改造后可稳定表达细胞表面人B2M,广泛用于机制研究、高通量筛选、药物靶标验证及其他相关领域。
| Host Cell | HEK293 | Gene | FcRn (FCGRT & B2M) | | Size | >5x10^6 cells per vial | Storage | Liquid nitrogen | | Species | Human | Shipment | Dry Ice | | Stability | Validated for at least 10 passages | | Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. | | Applications | Widely used in mechanisms study, high-throughput screening, drug target validation and others. | | Revival | After retrieving the cells from the liquid nitrogen tank, rapidly thaw them in a 37°C water bath. Transfer contents into a tube with pre-warmed media. Centrifuge cells and seed into a 25 cm^2 flask containing pre-warmed media. |

产品验证

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