货号: | ERBB2-CHR17-20-ORGR | 规格: | |
品牌: | 热销产品 | 价格: | ¥ |
产品分类: | 热销产品 | 研究领域: | |
CAS编号: | 分子量: | ||
分子式: | 别名: | ||
储存条件: | 运输条件: | ||
货期: | 应用: | ||
说明书: | 备注: | ||
产品描述 | |||
ERBB2/Con17 FISH Probe ERBB2-CHR17-20-ORGR 20 (40 μL) ERBB2-CHR17-20-REGR 20 (40 μL) ERBB2-CHR17-20-GOGR 20 (40 μL) Brand:Empire Genomics Our ERBB2/Control 17 probe is designed to detect ERBB2 amplifications and deletions. The probe comes labeled in orange and green, but can be customized to meet your needs. Gene Background: ERBB2 is a member of the receptor tyrosine kinase family, a subset of receptor proteins that bind epidermal growth factor (EGF).1 ERBB2 doesn’t have a binding domain itself, but stabilizes the configurations of other receptor proteins, making it easier for EGF to latch on.1 ERBB2 is involved in a lengthy list of important signaling cascades, as EGF is a ubiquitous mitogenic factor that stimulates cell growth in many tissue types.2 ERBB2’s oncogenic effects first came to light in 1987, when it was found to play a major role in breast cancer metastasis.3 The gene remains primarily associated with breast cancer (20-30% of breast cancer patients have amplified ERBB2) but it’s now also considered an important oncogene in uterine, gastric, pancreatic, colorectal and endometrial cancer, among others. Product Details SKU Test Kits Buffer ERBB2-CHR17-20-ORGR (Standard Design) 20 (40 μL) 200 μL ERBB2-CHR17-20-REGR 20 (40 μL) 200 μL ERBB2-CHR17-20-GOGR 20 (40 μL) 200 μL |