产品名称
Anti-Human C4d Antibody (Eagle Biosciences, CAT# BI-RC4D)
货号: |
BI-RC4D |
规格: |
96T or More |
品牌: |
Eagle Biosciences |
价格: |
¥请询价 |
产品分类: |
ELISA试剂盒 |
研究领域: |
酶联免疫吸附实验 |
CAS编号: |
|
分子量: |
|
分子式: |
|
别名: |
|
储存条件: |
4℃ |
运输条件: |
4℃ |
货期: |
3-4周 |
应用: |
ELISA |
说明书: |
|
备注: |
|
产品描述 |
The Anti-Human C4d antibody is described by the majority of publications as an important marker in kidney transplantation but also in heart, liver, and other transplants. Circulating alloantibodies encounter the grafted endothelium as the first target. Living endothelial cells can rapidly eliminate bound antibodies from the cell surface by “capping”, “shedding” or “internalisation”. C4d is the degradation product of the activated complement factor C4, a component of the classical complement cascade, which is typically initiated by binding of antibodies to specific target molecules. Detection of C4d is regarded as an indirect sign, a “footprint” of an antibody response against the allograft. |