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产品名称 APC anti-human CD107a (LAMP-1) Antibody(Biolegend 328620 现货特卖)
货号: 328620 规格: 100 tests
品牌: 热销产品 价格:
产品分类: 特价奥特莱斯专区 研究领域:
CAS编号: 分子量:
分子式: 别名:
储存条件: The antibody solution should be stored undiluted between 2°C and 8°C 运输条件:
货期: 应用:
说明书: 备注:
产品描述


h4a3_apc_110308.Jpg

维百奥生物库存现货,特价销售APC anti-human CD107a (LAMP-1) Antibody

| 产品信息

品名:APC anti-human CD107a (LAMP-1) Antibody

品牌:Biolegend

货号:328620

规格:100 tests


产品描述

CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.


产品属性

CloneH4A3
Other NamesLysosome-Associated Membrane Protein 1, LGP-120, LAMP-1
IsotypeMouse IgG1, κ
Verified ReactivityHuman
Antibody TypeMonoclonal
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
PreparationThe antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Storage & HandlingThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Recommended UsageEach lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation LaserRed Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: Western blotting8, immunohistochemical staining2, immunofluorescence5,7, and immunoprecipitation5.

This antibody is specific to human LAMP-1. Positive control: Hela cells; LAMP-1 molecular weight appears to be at ~110 kDa on the gel due to high glycosylation.








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