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产品名称 Human IL-4 Recombinant Protein(PeproTech 200-04-50ug 现货特卖)
货号: 200-04-50ug 规格: 50ug
品牌: 热销产品 价格:
产品分类: 特价奥特莱斯专区 研究领域:
CAS编号: 分子量:
分子式: 别名:
储存条件: -20°C 运输条件: Ambient
货期: 应用:
说明书: 备注:
产品描述


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维百奥生物库存现货,特价销售Human IL-4 Recombinant Protein 50ug

| 产品信息

品名:Human IL-4 Recombinant Protein

品牌:Peprotech

货号:200-04-50ug

规格:50ug


产品属性

种属Human形式Lyophilized
Expression SystemE. coli纯化类型purified
分子量15.1 kDa内含物no preservative
内毒素浓度<1 EU/µg保存条件-20°C
偶联物Unconjugated运输条件Ambient
已发表种属Chicken, Dog, Human, Mouse, Pig, Rabbit, Rat
纯度≥ 98% by SDS-PAGE gel and HPLC analyses.
氨基酸序列MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
活性The ED50 as determined by the dose-dependent stimulation of human TF-1 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10^6 units/mg.


产品描述

Recombinant Human IL-4 is a 15.1 kDa globular protein containing 130 amino acid residues.


| 耙标信息

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.






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